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Article

Comparative Aspects of Immunoglobulin Gene Rearrangement Arrays in Different Species.

Frontiers in immunology - 1 Jan 2022

Sinkora Marek, Stepanova Katerina, Butler John E, Sinkora Marek, Sinkora Simon, Sinkorova Jana

Abstract excerpt

Studies in humans and mice indicate the critical role of the surrogate light chain in the selection of the productive immunoglobulin repertoire during B cell development. However, subsequent studies using mutant mice have also demonstrated that alternative pathways are allowed. Our recent investigation has shown that some species, such as pig, physiologically use preferential rearrangement of authentic light...

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Identifiers

PMID: 35222402
DOI: 10.3389/fimmu.2022.823145
PMCID: PMC8873125

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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