Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CYP450 2D6 and 2C19 genotypes in ADHD: not related with treatment resistance but with over-representation of 2C19 ultra-metabolizers.

Drug metabolism and personalized therapy - 1 Sept 2022

Kutuk Meryem Ozlem, Tufan Ali Evren, Topal Zehra, Acikbas Ufuk, Guler Gulen, Karakas Bahriye, Basaga Huveyda, Kilicaslan Fethiye, Altintas Ebru, Aka Yeliz, Kutuk Ozgur

Abstract excerpt

OBJECTIVES: Cytochrome P450 (CYP450) is a major enzyme system involved in drug metabolism as well as regulation of brain function. Although individual variability in CYP enzymes have been studied in terms of personality traits and treatment effects, no study up to now evaluated CYP polymorphisms in children with attention deficit/hyperactivity disorder (ADHD). We aimed to define the genetic profiles of CYP2D6 and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Attention Deficit Disorder with Hyperactivity
Share to Child

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP2C19

Share to Cytochrome P-450 CYP2D6

Share to Genotype

Source

Identifiers

PMID: 35218180
DOI: 10.1515/dmpt-2021-0163

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CYP450 2D6 and 2C19 genotypes in ADHD: not related with treatment resistance but with over-representation of 2C19 ultra-metabolizers.PMID 35218180Read ↗

Pharmacogenetics of Cytochrome P450 Enzymes in American Indian and Caucasian Children Admitted to a Psychiatric Hospital.Semantic proximity Read ↗

Clinical Pharmacogenetics Implementation Consortium Guideline for <scp>Cytochrome P450 (<i>CYP</i>)</scp><i>2D6</i> Genotype and Atomoxetine TherapySemantic proximity Read ↗

Genetic Polymorphisms <em>CYP3A4*22</em>, <em>CYP3A5*3</em>, and CYP2D6 Predicted Phenotype are not Associated with Antipsychotic Treatment Outcomes in Neurotypical Prepubertal Boys with Conduct DisordersSemantic proximity Read ↗

CYP2D6 variation, behaviour and psychopathology: implications for pharmacogenomics-guided clinical trials.Semantic proximity Read ↗

An ADHD 6-year-old child ultrarapid metabolizer for CYP2D6.Semantic proximity Read ↗

[Pharmacoresistance to psychotropic drugs in children and adolescents: Pharmacogenetic anomalies of cytochrome P450 2D6].Semantic proximity Read ↗

Phenotyping and genotyping of drug metabolism to guide pharmacotherapy in psychiatry.Semantic proximity Read ↗

Influence of genetic variants of CYP2D6, CYP2C9, CYP2C19 and CYP3A4 on antiepileptic drug metabolism in pediatric patients with refractory epilepsy.Semantic proximity Read ↗

Frequencies of CYP2C19 and CYP2D6 gene variants in a German inpatient sample with mood and anxiety disorders.Semantic proximity Read ↗

Individualized atomoxetine response and tolerability in children with ADHD receiving different dosage regimens: the need for CYP2D6 genotyping and therapeutic drug monitoring to dance together.Semantic proximity Read ↗

Drug-metabolizing enzyme genotypes and aggressive behavior treatment response in hospitalized pediatric psychiatric patients.Semantic proximity Read ↗

[The relevance of genetically determined polymorphism CYP2D6 in psychopharmacology; the relationship between genotype and phenotype].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.