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Article

SALL4 Oncogenic Function in Cancers: Mechanisms and Therapeutic Relevance

12 Feb 2022

Abstract excerpt

SALL4, a member of the SALL family, is an embryonic stem cell regulator involved in self-renewal and pluripotency. Recently, SALL4 overexpression was found in malignant cancers, including lung cancer, hepatocellular carcinoma, breast cancer, gastric cancer, colorectal cancer, osteosarcoma, acute myeloid leukemia, ovarian cancer, and glioma. This review updates recent advances of our knowledge of the biology of...

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PMID: 35216168
DOI: 10.3390/ijms23042053

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