Article
Genetic polymorphisms in CYP2B6 may be associated with lung cancer risk in the Chinese Han population.
Expert review of respiratory medicine - 1 Dec 2023
Ma Xiaoya, Zang Xufeng, Yang Leteng, Zhou Wenqian, Li Yujie, Wei Jie, Guo Jinping, Han Junhui, Liang Jing, Jin Tianbo
Abstract excerpt
BACKGROUND: Our study aimed to elucidate the association between single nucleotide polymorphisms (SNPs) in CYP2B6 gene and susceptibility to lung cancer (LC). METHODS: Five SNPs in CYP2B6 were genotyped in Chinese Han population (507 cases and 505 controls) utilizing Agena MassARRAY. The relationship between these SNPs and LC susceptibility was assessed using odds ratios, 95% confidence intervals, and χ2 tests....
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