Article
Flow Cytometry and Molecular Techniques Could Complement Morphological Detection of Leukemic Infiltration in Ascitic Fluids: A Case Report.
Medicina (Kaunas, Lithuania) - 10 Feb 2022
Martínez-Alfonzo Inés, Láinez-González Daniel, Solán-Blanco Laura, Franganillo-Suarez Aida, Cornejo José I, Garcia-Lopez Amanda, Martín-Herrero Sara, Castaño-Bonilla Tamara, Salgado-Sánchez Rocío, Arquero-Portero Teresa, Cortti-Ferrari María J, Llamas-Sillero Pilar, Alonso-Dominguez Juan M
Abstract excerpt
Extramedullary involvement of acute myeloid leukemia (AML) is infrequent, and ascitic infiltration is even more unusual. We present a case of a 48-year-old woman diagnosed with NPM1-mutated AML that debuted with ascites, for which morphological studies of the ascitic fluid did not detect leukemic infiltration, maybe due to technical problems in the sample preparation. Multiparameter flow cytometry (MFC) detected...
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