Article
MiR-182-5p Modulates Prostate Cancer Aggressive Phenotypes by Targeting EMT Associated Pathways.
Biomolecules - 22 Jan 2022
Souza Marilesia Ferreira, Cólus Ilce Mara Syllos, Fonseca Aline Simoneti, Antunes Valquíria Casanova, Kumar Deepak, Cavalli Luciane Regina
Abstract excerpt
Prostate cancer (PCa) is a clinically heterogeneous disease, where deregulation of epigenetic events, such as miRNA expression alterations, are determinants for its development and progression. MiR-182-5p, a member of the miR-183 family, when overexpressed has been associated with PCa tumor progression and decreased patients' survival rates. In this study, we determined the regulatory role of miR-182-5p in...
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