Article
Case Report of Small Cell Carcinoma of the Ovary, Hypercalcemic Type (Ovarian Rhabdoid Tumor) with SMARCB1 Mutation: A Literature Review of a Rare and Aggressive Condition.
Current oncology (Toronto, Ont.) - 18 Jan 2022
Simões Maria Fernanda Evangelista, da Costa Alexandre André Balieiro Anastácio, Silva Tullio Novaes, Fernandes Lizieux, Bovolim Graziele, Torrezan Giovana Tardin, Carraro Dirce Maria, Baiocchi Glauco, Menezes Ademir Narcizo Oliveira, Santana Dos Santos Elizabeth, De Brot Louise
Abstract excerpt
Small cell carcinoma of the ovary, hypercalcemic type (SCCOHT) is a rare and aggressive condition that is associated with the SMARCA4 mutation and has a dismal prognosis. It is generally diagnosed in young women. Here, we report a case of a young woman with SCCOHT harboring a rare molecular finding with a highly aggressive biological behavior. The patient had a somatic SMARCB1 mutation instead of an expected...
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