Article
Phenotypes of mutations related to voltage-dependent sodium channels on children and adolescents.
Journal of biochemical and molecular toxicology - 1 Apr 2022
Ferreira Andressa Coelho, Dias-Filho Carlos Alberto Alves, de Jesus Silva Soares Junior Nivaldo, Dias Carlos José, Monteiro Sally Cristina Moutinho, Andrade Rafael Martins, Mostarda Cristiano Teixeira
Abstract excerpt
Cardiac channelopathies are a heterogeneous group of inherited cardiac diseases that are associated with mutations in the genes that encode the expression of cardiac ion channels. In view of this, it can be mentioned that the main hereditary arrhythmias in children and adolescents, caused by dysfunction of the ion channels, are Brugada Syndrome (BrS) and Long QT Syndrome (LQTS). However, few studies address the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.