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Article

A New Era in Endothelial Injury Syndromes: Toxicity of CAR-T Cells and the Role of Immunity.

International journal of molecular sciences - 29 May 2020

Gavriilaki Eleni, Sakellari Ioanna, Gavriilaki Maria, Anagnostopoulos Achilles

Abstract excerpt

Immunotherapy with chimeric antigen receptor T (CAR-T cells) has been recently approved for patients with relapsed/refractory B-lymphoproliferative neoplasms. Along with great efficacy in patients with poor prognosis, CAR-T cells have been also linked with novel toxicities in a significant portion of patients. Cytokine release syndrome (CRS) and neurotoxicity present with unique clinical phenotypes that have not...

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Identifiers

PMID: 32485958
DOI: 10.3390/ijms21113886
PMCID: PMC7312228

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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