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The potential role of methyltransferase-like 5 in deficient mismatch repair of uterine corpus endometrial carcinoma

15 Feb 2022

Abstract excerpt

To explore the potential function of methyltransferase-like 5 (METTL5) in uterine corpus endometrial carcinoma (UCEC) and verify the relationship between deficient DNA mismatch repair (MMR) and METTL5. We used bioinformatics to predict the possible role of METTL5 and molecular biology methods to analyze METTL5 expression. We observed UCEC proliferation, development, and apoptosis using a METTL5 knockdown...

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PMID: 35166644
DOI: 10.1080/21655979.2022.2036912

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