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Article

Impact of DNA mismatch repair system alterations on human fertility and related treatments.

Journal of Zhejiang University. Science. B - 1 Jan 2016

Hu Min-hao, Liu Shu-yuan, Wang Ning, Wu Yan, Jin Fan

Abstract excerpt

DNA mismatch repair (MMR) is one of the biological pathways, which plays a critical role in DNA homeostasis, primarily by repairing base-pair mismatches and insertion/deletion loops that occur during DNA replication. MMR also takes part in other metabolic pathways and regulates cell cycle arrest. Defects in MMR are associated with genomic instability, predisposition to certain types of cancers and resistance to...

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Identifiers

PMID: 26739522
DOI: 10.1631/jzus.B1500162
PMCID: PMC4710836

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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