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Article

COMT Val/Met and Psychopathic Traits in Children and Adolescents: A Systematic Review and New Evidence of a Developmental Trajectory toward Psychopathy.

International journal of molecular sciences - 4 Feb 2022

Kant Tuana, Koyama Emiko, Zai Clement C, Beitchman Joseph H, Kennedy James L

Abstract excerpt

Psychopathic traits in youth may lead to adult criminal behaviors/psychopathy. The Val158Met polymorphism of catechol-O-methyltransferase (COMT) may influence the risk for psychopathy-related behaviors, while acting as a biomarker for predicting treatment response to dopaminergic medications. The literature shows inconsistent findings, making the interpretation of COMT's role difficult. The aims of this article...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Catechol O-Methyltransferase

Share to Genetic Predisposition to Disease

Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 35163702
DOI: 10.3390/ijms23031782
PMCID: PMC8836546

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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