Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Single Nucleotide Polymorphism of TWIST2 May Be a Modifier for the Association between High-Density Lipoprotein Cholesterol and Blood Lead (Pb) Level.

International journal of environmental research and public health - 26 Jan 2022

Yang Chen-Cheng, Dai Chia-Yen, Luo Kuei-Hau, Lee Kuo-Wei, Wu Cheng-Hang, Hung Chih-Hsing, Chuang Hung-Yi, Kuo Chao-Hung

Abstract excerpt

The association between lead (Pb) exposure and lower high-density lipoprotein cholesterol (HDL-C) was reported; however, the mechanism was unclear. Our purpose was to investigate the association of Pb, lipid profile, and to study the associated SNPs using a genome-wide association study (GWAS). A total of 511 participants were recruited to check blood Pb levels, lipid profile, and genotypes with Taiwan Biobank...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cholesterol, HDL
Share to Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lipids

Share to Polymorphism, Single Nucleotide

Share to Repressor Proteins

Share to Twist-Related Protein 1

Source

Open in PubMed Open full text

Identifiers

PMID: 35162374
DOI: 10.3390/ijerph19031352
PMCID: PMC8834775

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Single Nucleotide Polymorphism of TWIST2 May Be a Modifier for the Association between High-Density Lipoprotein Cholesterol and Blood Lead (Pb) Level.PMID 35162374Read ↗

Exome-wide association study identifies genetic polymorphisms of C12orf51, MYL2, and ALDH2 associated with blood lead levels in the general Korean population.Semantic proximity Read ↗

[Lead exposure markers and related susceptibility genes based on different people].Semantic proximity Read ↗

Polymorphism of Metallothionein 2A Modifies Lead Body Burden in Workers Chronically Exposed to the Metal.Semantic proximity Read ↗

The association of the blood lead level and serum lipid concentrations may be modified by the genetic combination of the metallothionein 2A polymorphisms rs10636 GC and rs28366003 AA.Semantic proximity Read ↗

Genome-wide association and Mendelian randomization study of blood copper levels and 213 deep phenotypes in humans.Semantic proximity Read ↗

Interplay analysis of lead exposure with key cardiovascular gene polymorphisms on blood pressure in a cross-sectional study of occupational workers.Semantic proximity Read ↗

PLCH2 gene modifies the U-shaped association between environmental selenium exposure and blood total cholesterol: A gene-environment interaction study.Semantic proximity Read ↗

Interactions between multiple serum metals and genetic variants for type 2 diabetes risk: A prospective Chinese cohort studySemantic proximity Read ↗

Evaluation of divalent metal transporter 1 (DMT1) (rs224589) polymorphism on blood lead levels of occupationally exposed individuals.Semantic proximity Read ↗

The association of metallothionein-4 gene polymorphism and renal function in long-term lead-exposed workers.Semantic proximity Read ↗

Human-Relevant Lead Exposure During Differentiation Alters the Transcriptomic Profile of Human Induced Pluripotent Stem Cell-Derived CardiomyocytesSemantic proximity Read ↗

Blood lead levels and bladder cancer among US participants: NHANES 1999–2018Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.