Article
PLCH2 gene modifies the U-shaped association between environmental selenium exposure and blood total cholesterol: A gene-environment interaction study.
Ecotoxicology and environmental safety - 15 Apr 2026
Nie Xiuquan, Mu Ge, Guo Yanjun, Yang Shijie, Wang Xing, Ye Zi, Tan Qiyou, Wang Mengyi, Zhou Min, Ma Jixuan, Chen Weihong
Abstract excerpt
Exposure to excessive selenium (Se) is hazardous to human health, while Se is also an essential trace element. Therefore, exploring the appropriate exposure dose of Se has received widespread attention. Currently, the impact of Se exposure on blood lipids remains uncertain, and the potential mechanism is still unclear. Evidence from our earlier study pointed to PLCH2 as a potentially pivotal element in the...
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