Interplay analysis of lead exposure with key cardiovascular gene polymorphisms on blood pressure in a cross-sectional study of occupational workers.

doi:10.1038/s41598-024-77194-z

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Interplay analysis of lead exposure with key cardiovascular gene polymorphisms on blood pressure in a cross-sectional study of occupational workers.

Scientific reports - 22 Nov 2024

Ou Xiaoyan, Xiao Chen, Jiang Jun, Liu Xinxia, Liu Lili, Lu Yao, Zhang Weipeng, He Yun, Zhao Zhiqiang

Abstract excerpt

An increasing number of studies have shown that lead is an important cardiovascular risk factor, but the impact of cardiovascular related gene polymorphisms on lead induced cardiovascular diseases is still unclear. To assess the interaction of lead exposure and related key cardiovascular regulating gene polymorphisms on blood pressure traits, three single-nucleotide polymorphisms including NOTCH1 rs3124591,...

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PMID: 39578479
DOI: 10.1038/s41598-024-77194-z
PMCID: PMC11584784

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