Article
Mutation Profiling of Intracranial Myxopapillary Ependymoma by Next Generation DNA Sequencing.
The Gulf journal of oncology - 1 Sept 2021
Taher Mohiuddin M, Alhussini Abdulaziz Abdulnasser, Saeed Muhammad, Athar Mohammad, Bantan Najwa Abdalkabeer A, Jastania Raid A, Balkhoyour Kamal Bakour, Nageeti Tahani H
Abstract excerpt
OBJECTIVES: Primary intracranial myxopapillary ependymomas (MPE) are very rare. In order to determine genomic changes in an intracranial MPE, we analyzed its mutation patterns by next generation DNA sequencing. METHODS: Tumor DNA was sequenced using an Ion PI v3 chip on Ion Proton instrument and the data were analyzed by Ion Reporter 5.6. RESULTS: In this tumor, NGS generated 6,298, 354 mapped reads using the Ion...
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