Article
Long-term dynamic shifts in genomic base content and evolutionary trajectories of SARS-CoV-2 variants.
Journal of medical virology - 1 Oct 2023
Li Xinjie, Zhang Yuqi, Wang Jie, Han Jun, Shen Tao
Abstract excerpt
The rapid spread and remarkable mutations of SARS-CoV-2 variants, particularly Omicron, necessitate an understanding of their evolutionary characteristics. In this study, we analyzed representative high-quality whole-genome sequences of 2008 SARS-CoV-2 variants to explore long-term dynamic changes in genomic base (especially GC) content and variations during viral evolution. Our results demonstrated a highly...
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