Article
Enteric nervous system modulation of luminal pH modifies the microbial environment to promote intestinal health.
PLoS pathogens - 1 Feb 2022
Hamilton M Kristina, Wall Elena S, Robinson Catherine D, Guillemin Karen, Eisen Judith S
Abstract excerpt
The enteric nervous system (ENS) controls many aspects of intestinal homeostasis, including parameters that shape the habitat of microbial residents. Previously we showed that zebrafish lacking an ENS, due to deficiency of the sox10 gene, develop intestinal inflammation and bacterial dysbiosis, with an expansion of proinflammatory Vibrio strains. To understand the primary defects resulting in dysbiosis in sox10...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.