Article

Pathogen and host adapt pH responses during enteric infection

2024-01-05

Abstract excerpt

Enteric pathogens navigate distinct regional micro-environments within the intestine which cue important adaptive behaviours. We investigated the response of Citrobacter rodentium , a model of human pathogenic Escherichia coli infection, to regional gastrointestinal pH. We found that small intestinal pH (4.4-4.8) triggered virulence gene expression and altered cell morphology, supporting initial intestinal attac...

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Identifiers and source

Literature Corpus work: 930a938f-3698-591f-899e-01f5b130c70a
DOI: 10.1101/2024.01.05.573998

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