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Teleocidin-producing genotype of Streptomyces clavuligerus ATCC 27064.

Applied microbiology and biotechnology - 1 Feb 2022

Pivk Lukančič Petra, Drčar Tjaša, Bruccoleri Robert, Črnugelj Martin, Mrak Peter

Abstract excerpt

Streptomyces clavuligerus is an industrially important producer of clavulanic acid (CA), a β-lactamase inhibitor which is used together with amoxicillin in one of the most widely prescribed antibacterial medicines, the co-amoxiclav. In a mid-eighties ATCC vial of S. clavuligerus ATCC 27064 culture, we have found a new genotype, which was apparently lost from the subsequent ATCC collection stocks, and has remained...

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Identifiers

PMID: 35138454
DOI: 10.1007/s00253-022-11805-5
PMCID: PMC8882083

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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