Article
Predicting the genomic resolution of bulk segregant analysis.
G3 (Bethesda, Md.) - 4 Mar 2022
Shen Runxi, Messer Philipp W
Abstract excerpt
Bulk segregant analysis is a technique for identifying the genetic loci that underlie phenotypic trait differences. The basic approach is to compare two pools of individuals from the opposing tails of the phenotypic distribution, sampled from an interbred population. Each pool is sequenced and scanned for alleles that show divergent frequencies between the pools, indicating potential association with the observed...
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