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Article

Maternal effect on intelligence in fragile X males and females.

American journal of medical genetics - 1 Jan 2000

Van Dyke D L, Weiss L

Abstract excerpt

If the mother is the fragile X gene carrier, her daughters (and sons) with the mutation are at high risk of mental retardation. If the father is the (clinically unaffected) carrier, his daughters are normal. This is strong evidence for a maternal effect. The decreased penetrance and variable expressivity in fra(X) offspring of carriers could be related, at least in part, to variabile expression or availability of...

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Source

Identifiers

PMID: 3513574
DOI: 10.1002/ajmg.1320230163

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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