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Article

Identification of SCN7A as the key gene associated with tumor mutation burden in gastric cancer.

BMC gastroenterology - 5 Feb 2022

Li Wenjie, Zhou Kezhi, Li Mengting, Hu Qian, Wei Wanhui, Liu Lan, Zhao Qiu

Abstract excerpt

OBJECTIVE: Previous studies have shown that tumor mutation burden (TMB) in cancer is associated with prognosis. The purpose of this study is to identify TMB related genes in gastric cancer (GC) and to explore their prognostic value. METHODS: In our research, weighted gene coexpression network analysis (WGCNA) algorithm was used to cluster the most relevant TMB modules in the Cancer Genome Atlas (TCGA) database....

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Identifiers

PMID: 35123417
DOI: 10.1186/s12876-022-02112-4
PMCID: PMC8817579

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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