Article
Identification of Hub Genes in Gastric Cancer with High Heterogeneity Based on Weighted Gene Co-Expression Network.
Critical reviews in eukaryotic gene expression - 1 Jan 2020
Dong Zhe, Pei Shengnan, Zhao Yan, Guo Shuai, Wang Yue
Abstract excerpt
Intra-tumor heterogeneity (ITH) plays an important role in the therapeutic resistance and prognosis of gastric cancer (GC), but there are no effective methods to detect it. The purpose of this study was to apply the mutant-allele tumor heterogeneity (MATH) algorithm to reveal the relationship between ITH and clinical features, and to use weighted gene co-expression network analysis (WGCNA) to search hub genes....
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