Article
Treatment by biomarker-informed endotype vs guideline care in children with difficult-to-treat asthma.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology - 1 May 2022
Guilbert Theresa W, Biagini Jocelyn M, Ramsey Rachelle R, Keidel Kristina, Curtsinger Kristi, Kroner John W, Durrani Sandy R, Stevens Mariana, Pilipenko Valentina, Martin Lisa J, Kercsmar Carolyn M, Hommel Kevin, Hershey Gurjit K Khurana
Abstract excerpt
BACKGROUND: Asthma is heterogeneous, contributing to difficulty in disease management. OBJECTIVE: To develop a biomarker-informed treatment model for difficult-to-treat (DTT) asthma and conduct a pilot feasibility study. METHODS: School-aged children (n = 21) with DTT asthma were enrolled and completed 3 medical visits (V1-V3). V2 and V3 were completed approximately 3.5 months and 12 months after V1,...
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