Article
Asthma characteristics and biomarkers from the Airways Disease Endotyping for Personalized Therapeutics (ADEPT) longitudinal profiling study.
Respiratory research - 17 Nov 2015
Silkoff P E, Strambu I, Laviolette M, Singh D, FitzGerald J M, Lam S, Kelsen S, Eich A, Ludwig-Sengpiel A, Hupp G C, Backer V, Porsbjerg C, Girodet P O, Berger P, Leigh R, Kline J N, Dransfield M, Calhoun W, Hussaini A, Khatri S, Chanez P, Susulic V S, Barnathan E S, Curran M, Das A M, Brodmerkel C, Baribaud F, Loza M J
Abstract excerpt
BACKGROUND: Asthma is a heterogeneous disease and development of novel therapeutics requires an understanding of pathophysiologic phenotypes. The purpose of the ADEPT study was to correlate clinical features and biomarkers with molecular characteristics, by profiling asthma (NCT01274507). This report presents for the first time the study design, and characteristics of the recruited subjects. METHODS: Patients...
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