Whole genome analysis identifies intra-serotype recombinants and positive selection sites of dengue virus in mainland China from 2015 to 2020.

doi:10.1016/j.virusres.2022.198705

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Whole genome analysis identifies intra-serotype recombinants and positive selection sites of dengue virus in mainland China from 2015 to 2020.

Virus research - 2 Apr 2022

Zhu Xiaoli, Chen Wanxin, Ma Chunli, Wang Xin, Sun Jing, Nie Jianyun, Shi Jiandong, Hu Yunzhang

Abstract excerpt

Immune pressure can select for escape mutants that can become epidemiologically relevant. Thus, surveillance of recombinants and positively selected mutants of the dengue virus (DENV) are vital for preventing and controlling the dengue fever outbreak. However, little is known about recombinants and positively selected mutants of circulating DENV strains in mainland China. In this study, those variants with...

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PMID: 35121087
DOI: 10.1016/j.virusres.2022.198705

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