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Evolutionary and phylodynamic analyses of Dengue virus serotype I in Guangdong Province, China, between 1985 and 2015.

Virus research - 2 Sept 2018

Bai Zhijun, Liu Li Cheng, Jiang Liyun, Luo Lei, Feng Huahua, Lin Peng, Jing Qinglong, Xiao Xincai, Zhou Huiqiong, Su Wenzhe, Cao Yimin, Li Yilan, Cao Qing, Chen Weijun, Di Biao, Yang Zhicong

Abstract excerpt

To determine the evolutionary and phylodynamic history of DENV-1 in Guangdong, the strains detected between 1985 and 2015 were determined with phylogenetic and Bayesian analyses of the E gene. Three DENV-1 genotypes (I, V, and VI) were circulating in Guangdong, and genotype I was detected most frequently. The evolutionary rate of DENV-1 was estimated to be 1.03 × 10-3 nucleotide substitutions/site/year. The most...

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PMID: 29990510
DOI: 10.1016/j.virusres.2018.07.005

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