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Article

A special prognostic indicator: tumor mutation burden combined with immune infiltrates in lung adenocarcinoma with TP53 mutation

1 Sept 2021

Abstract excerpt

Background: TP53 mutation (TP53mut) is significantly associated with immunotherapy response in lung adenocarcinoma (LUAD), but not an ideal independent prognostic predictor for it. Here, we investigated a novel potential biomarker and constructed a model for prognostic prediction in LUAD TP53mut patients. Methods: 469 LUAD samples retrieved from The Cancer Genome Atlas database were divided into TP53wt (wild-type...

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PMID: 35116695
DOI: 10.21037/tcr-21-565

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