Article
Heterozygous Dcc Mutant Mice Have a Subtle Locomotor Phenotype.
eNeuro - 1 Jan 2000
Thiry Louise, Lemaire Chloé, Rastqar Ali, Lemieux Maxime, Peng Jimmy, Ferent Julien, Roussel Marie, Beaumont Eric, Fawcett James P, Brownstone Robert M, Charron Frédéric, Bretzner Frédéric
Abstract excerpt
Axon guidance receptors such as deleted in colorectal cancer (DCC) contribute to the normal formation of neural circuits, and their mutations can be associated with neural defects. In humans, heterozygous mutations in DCC have been linked to congenital mirror movements, which are involuntary movements on one side of the body that mirror voluntary movements of the opposite side. In mice, obvious hopping phenotypes...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.