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Article

Transmembrane channel-like (tmc) gene regulates Drosophila larval locomotion.

Proceedings of the National Academy of Sciences of the United States of America - 28 Jun 2016

Guo Yanmeng, Wang Yuping, Zhang Wei, Meltzer Shan, Zanini Damiano, Yu Yue, Li Jiefu, Cheng Tong, Guo Zhenhao, Wang Qingxiu, Jacobs Julie S, Sharma Yashoda, Eberl Daniel F, Göpfert Martin C, Jan Lily Yeh, Jan Yuh Nung, Wang Zuoren

Abstract excerpt

Drosophila larval locomotion, which entails rhythmic body contractions, is controlled by sensory feedback from proprioceptors. The molecular mechanisms mediating this feedback are little understood. By using genetic knock-in and immunostaining, we found that the Drosophila melanogaster transmembrane channel-like (tmc) gene is expressed in the larval class I and class II dendritic arborization (da) neurons and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 27298354
DOI: 10.1073/pnas.1606537113
PMCID: PMC4932980

Genes

TMC1
TMC2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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