Article
Neural function in DCC mutation carriers with and without mirror movements.
Annals of neurology - 1 Mar 2019
Vosberg Daniel E, Beaulé Vincent, Torres-Berrío Angélica, Cooke Danielle, Chalupa Amanda, Jaworska Natalia, Cox Sylvia M L, Larcher Kevin, Zhang Yu, Allard Dominique, Durand France, Dagher Alain, Benkelfat Chawki, Srour Myriam, Tampieri Donatella, La Piana Roberta, Joober Ridha, Lepore Franco, Rouleau Guy, Pascual-Leone Alvaro, Fox Michael D, Flores Cecilia, Leyton Marco, Théoret Hugo
Abstract excerpt
OBJECTIVE: Recently identified mutations of the axon guidance molecule receptor gene, DCC, present an opportunity to investigate, in living human brain, mechanisms affecting neural connectivity and the basis of mirror movements, involuntary contralateral responses that mirror voluntary unilateral actions. We hypothesized that haploinsufficient DCC+/- mutation carriers with mirror movements would exhibit decreased...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.