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Chromosome counting in the mouse zygote using low‐invasive super‐resolution live‐cell imaging

3 Feb 2022

Abstract excerpt

In preimplantation embryos, an abnormal chromosome number causes developmental failure and a reduction in the pregnancy rate. Conventional chromosome testing methods requiring biopsy reduce the risk of associated genetic diseases; nevertheless, the reduction in cell number also reduces the pregnancy rate. Therefore, we attempted to count the chromosomes in mouse embryos using super-resolution live-cell imaging as...

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PMID: 35114033
DOI: 10.1111/gtc.12925

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