Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The DNA methylome of cervical cells can predict the presence of ovarian cancer.

Nature communications - 1 Feb 2022

Barrett James E, Jones Allison, Evans Iona, Reisel Daniel, Herzog Chiara, Chindera Kantaraja, Kristiansen Mark, Leavy Olivia C, Manchanda Ranjit, Bjørge Line, Zikan Michal, Cibula David, Widschwendter Martin

Abstract excerpt

The vast majority of epithelial ovarian cancer arises from tissues that are embryologically derived from the Müllerian Duct. Here, we demonstrate that a DNA methylation signature in easy-to-access Müllerian Duct-derived cervical cells from women with and without ovarian cancer (i.e. referred to as the Women's risk IDentification for Ovarian Cancer index or WID-OC-index) is capable of identifying women with an...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to BRCA1 Protein
Share to BRCA2 Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cervix Uteri

Share to DNA Methylation

Share to Epigenome

Share to Epithelium

Share to Genetic Predisposition to Disease

Share to Ovarian Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 35105887
DOI: 10.1038/s41467-021-26615-y
PMCID: PMC8807742

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The DNA methylome of cervical cells can predict the presence of ovarian cancer.PMID 35105887Read ↗

Ovarian cancer detection by DNA methylation in cervical scrapingsSemantic proximity Read ↗

Unveiling DNA methylation: early diagnosis, risk assessment, and therapy for endometrial cancerSemantic proximity Read ↗

The WID-BC-index identifies women with primary poor prognostic breast cancer based on DNA methylation in cervical samples.Semantic proximity Read ↗

Virtues and Weaknesses of DNA Methylation as a Test for Cervical Cancer PreventionSemantic proximity Read ↗

Exploration of DNA methylation markers for diagnosis and prognosis of patients with endometrial cancerSemantic proximity Read ↗

Epigenetic reprogramming of fallopian tube fimbriae in BRCA mutation carriers defines early ovarian cancer evolution.Semantic proximity Read ↗

DNA methylation changes in ovarian cancer: Implications for early diagnosis, prognosis and treatmentSemantic proximity Read ↗

Clinical indications for host-cell DNA methylation markers in cervical screening and management of cervical intraepithelial neoplasia: A reviewSemantic proximity Read ↗

Methylomic Analysis of Ovarian Cancers Identifies Tumor-Specific Alterations Readily Detectable in Early Precursor LesionsSemantic proximity Read ↗

Detection of ovarian cancer using plasma cell-free DNA methylomesSemantic proximity Read ↗

Methylation and ovarian cancer: Can DNA methylation be of diagnostic use? (Review)Semantic proximity Read ↗

DNA methylation-based profiling of uterine neoplasms: a novel tool to improve gynecologic cancer diagnosticsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.