Article
Diagnostic accuracy of immunohistochemistry compared with molecular tests for detection of BRAF V600E mutation in ameloblastomas: Systematic review and meta-analysis.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology - 1 Mar 2022
Martins-de-Barros Allan Vinícius, Anjos Raíssa Soares Dos, Silva Caio César Gonçalves, Silva Emanuel Dias de Oliveira E, Araújo Fábio Andrey da Costa, Carvalho Marianne de Vasconcelos
Abstract excerpt
OBJECTIVE: The objective of this systematic review with meta-analysis was to critically evaluate the available data on sensitivity and specificity of IHC compared with molecular tests in the detection of BRAF V600E mutation in ameloblastomas. MATERIALS AND METHODS: This systematic review was performed based on the PRISMA statement and registered in Prospero (CRD42021259117). PubMed, Web of Science, Scopus, and...
Topics
- Ameloblastoma
- Biomarkers, Tumor
- Humans
- Immunohistochemistry
- Mutation
- Proto-Oncogene Proteins B-raf
- Sensitivity and Specificity