Article
Immunohistochemical analysis of BRAF V600E mutation in ameloblastomas.
Clinical oral investigations - 1 Feb 2019
do Canto Alan Motta, da Silva Marcelino Barbara Michaela Reis, Schussel Juliana Lucena, Wastner Bruna F, Sassi Laurindo Moacir, Corrêa Luciana, de Freitas Ronaldo Rodrigues, Hasséus Bengt, Kjeller Göran, Junior Celso Augusto Lemos, Braz-Silva Paulo Henrique
Abstract excerpt
OBJECTIVE: This study aimed to investigate the presence of BRAF V600E mutation in mandible ameloblastomas by correlating clinical and imaging data on the cases studied. METHODS: Eighty-four cases diagnosed as mandibular ameloblastoma were selected for analysis. The specimens were submitted to immunohistochemistry for detection of BRAF V600E mutated protein. Clinical-pathological data such as age, gender, tumour...
Topics
- Adult
- Ameloblastoma
- Biomarkers, Tumor
- Brazil
- Cross-Sectional Studies
- Female
- Humans
- Immunohistochemistry
- Male
- Mandibular Neoplasms
- Mutation
- Proto-Oncogene Proteins B-raf