Article
Identification of TIMELESS and RORA as key clock molecules of non-small cell lung cancer and the comprehensive analysis.
BMC cancer - 25 Jan 2022
Xian Haocheng, Li Yuan, Zou Boliang, Chen Yajuan, Yin Houqing, Li Xuejun, Pan Yan
Abstract excerpt
BACKGROUND: The incidence rate of non-small cell lung cancer (NSCLC) has been increasing worldwide, and the correlation of circadian rhythm disruption with a raised risk of cancer and worse prognosis has been shown by accumulating evidences recently. On the other hand, drug resistance and the impact of tumor heterogeneity have been inevitable in NSCLC therapy. These both lead to an urgent need to identify more...
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