Article
The contributing factors of resistance or sensitivity to epigenetic drugs in the treatment of AML.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico - 1 Jul 2022
Karimi Kelaye Shohre, Najafi Fatemeh, Kazemi Bahareh, Foruzandeh Zahra, Seif Farhad, Solali Saeed, Alivand Mohammad-Reza
Abstract excerpt
Drug resistance is the drug-effectiveness reduction in treatment and is a serious problem in oncology and infections. In oncology, drug resistance is a complicated process resulting from enhancing the function of a pump that transports drugs out of tumor cells, or acquiring mutations in drug target. Surprisingly, most drugs are very effective in the early stages, but the response to the drug wears off over time...
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