Article
Plasma Metagenomic Sequencing Expedites Diagnosis of Disseminated BCG in an Infant With IKBKB Mutation.
The Pediatric infectious disease journal - 1 May 2022
Taylor Margaret G, Nicholas Sarah K, Forbes Satter Lisa R, Martinez Caridad, Cameron Lindsay H
Abstract excerpt
BACKGROUND: Infants with inborn errors of immunity (IEI), born in countries where Bacillus-Calmette-Guerin (BCG) vaccination is recommended at birth, are at risk of developing infectious complications following vaccination. A prompt diagnosis of disseminated BCG infection in these infants is essential, as many will require stem cell transplantation (SCT) for the immunologic cure. In patients with IEI, the...
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