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Article

Recombinant IFN-γ1b Treatment in a Patient with Inherited IFN-γ Deficiency.

Journal of clinical immunology - 16 Feb 2024

Rosain Jérémie, Kiykim Ayca, Michev Alexandre, Kendir-Demirkol Yasemin, Rinchai Darawan, Peel Jessica N, Li Hailun, Ocak Suheyla, Ozdemir Pinar Gokmirza, Le Voyer Tom, Philippot Quentin, Khan Taushif, Neehus Anna-Lena, Migaud Mélanie, Soudée Camille, Boisson-Dupuis Stéphanie, Marr Nico, Borghesi Alessandro, Casanova Jean-Laurent, Bustamante Jacinta

Abstract excerpt

PURPOSE: Inborn errors of IFN-γ immunity underlie Mendelian susceptibility to mycobacterial disease (MSMD). Twenty-two genes with products involved in the production of, or response to, IFN-γ and variants of which underlie MSMD have been identified. However, pathogenic variants of IFNG encoding a defective IFN-γ have been described in only two siblings, who both underwent hematopoietic stem cell transplantation...

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Identifiers

PMID: 38363432
DOI: 10.1007/s10875-024-01661-5
PMCID: PMC10873451

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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