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Article

Mendelian randomization study of circulating lipids and biliary tract cancer among East Asians.

BMC cancer - 15 Mar 2022

Wang Jun, Zhuge Jinke, Feng Dongxu, Zhang Bo, Xu Jianying, Zhao Dongkang, Fei Zhewei, Huang Xia, Shi Wenjie

Abstract excerpt

BACKGROUND: Associations of High-density lipoprotein (HDL) cholesterol, low-density lipoprotein (LDL) cholesterol, total cholesterol (CHL), and triglyceride (TRG) concentrations with risk of biliary tract cancer (BtC) were conflicting in observational studies. We aim to investigate the causal link between circulating lipids and BtC using genetic information. METHODS: Single nucleotide polymorphisms of the four...

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Asian People
Biliary Tract Neoplasms
Cholesterol, HDL
Mendelian Randomization Analysis
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35291981
DOI: 10.1186/s12885-022-09382-x
PMCID: PMC8922750

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