Article
Haplotypes in the GC, CYP2R1 and CYP24A1 Genes and Biomarkers of Bone Mineral Metabolism in Older Adults.
Nutrients - 8 Jan 2022
Fernández-Araque Ana, Giaquinta-Aranda Andrea, Moreno-Sainz Carmelo, Martínez-Martínez María Cruz, Velasco-González Verónica, Sainz-Gil María, Martín-Arias Luis H, Carretero-Molinero Silvia, García-Hidalgo Miguel, Verde Zoraida
Abstract excerpt
Candidate gene studies have analyzed the effect of specific vitamin D pathway genes on vitamin D availability; however, it is not clear whether genetic variants also affect overall bone metabolism. This study evaluated the association between genetic polymorphisms in GC, CYP2R1 and CYP24A1 and serum levels of total 25(OH)D, iPTH and other mineral metabolism biomarkers (albumin, total calcium and phosphorus) in a...
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