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Article

Orofacial Cleft and Mandibular Prognathism-Human Genetics and Animal Models.

International journal of molecular sciences - 16 Jan 2022

Jaruga Anna, Ksiazkiewicz Jakub, Kuzniarz Krystian, Tylzanowski Przemko

Abstract excerpt

Many complex molecular interactions are involved in the process of craniofacial development. Consequently, the network is sensitive to genetic mutations that may result in congenital malformations of varying severity. The most common birth anomalies within the head and neck are orofacial clefts (OFCs) and prognathism. Orofacial clefts are disorders with a range of phenotypes such as the cleft of the lip with or...

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Identifiers

PMID: 35055138
DOI: 10.3390/ijms23020953
PMCID: PMC8779325

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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