Article
flopp: Extremely Fast Long-Read Polyploid Haplotype Phasing by Uniform Tree Partitioning.
Journal of computational biology : a journal of computational molecular cell biology - 1 Feb 2022
Shaw Jim, Yu Yun William
Abstract excerpt
Resolving haplotypes in polyploid genomes using phase information from sequencing reads is an important and challenging problem. We introduce two new mathematical formulations of polyploid haplotype phasing: (1) the min-sum max tree partition problem, which is a more flexible graphical metric compared with the standard minimum error correction (MEC) model in the polyploid setting, and (2) the uniform...
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