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Article

The redundancy and diversity between two novel PKC isotypes that regulate learning in Caenorhabditis elegans.

Proceedings of the National Academy of Sciences of the United States of America - 18 Jan 2022

Hiroki Shingo, Iino Yuichi

Abstract excerpt

The nematode Caenorhabditis elegans learns the concentration of NaCl and moves toward the previously experienced concentration. In this behavior, the history of NaCl concentration change is reflected in the level of diacylglycerol and the activity of protein kinase C, PKC-1, in the gustatory sensory neuron ASER and determines the direction of migration. Here, through a genetic screen, we found that the activation...

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Identifiers

PMID: 35027448
DOI: 10.1073/pnas.2106974119
PMCID: PMC8784152

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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