Article
Emergence of enterovirus 71 "double-recombinant" strains belonging to a novel genotype D originating from southern China: first evidence for combination of intratypic and intertypic recombination events in EV71.
Archives of virology - 1 Sept 2010
Yip Cyril C Y, Lau Susanna K P, Zhou Boping, Zhang Ming-Xia, Tsoi Hoi-Wah, Chan Kwok-Hung, Chen Xin-Chun, Woo Patrick C Y, Yuen Kwok-Yung
Abstract excerpt
Hand-foot-mouth disease due to enterovirus 71 (EV71) and coxsackievirus A16 (CA16) has recently caused large outbreaks in mainland China in 2008. We performed complete genome sequencing on two EV71 (SZ/HK08-5 and SZ/HK08-6) and two CA16 (SZ/HK08-3 and SZ/HK08-7) strains from patients in Shenzhen, China. Phylogenetic, similarity plot and bootscan analyses revealed recombination between EV71 genotypes B and C at...
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