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Article

Polycystic ovary syndrome as a plausible evolutionary outcome of metabolic adaptation

10 Jan 2022

Abstract excerpt

As a common endocrinopathy of reproductive-aged women, polycystic ovary syndrome (PCOS) is characterized by hyperandrogenism, oligo-anovulation and polycystic ovarian morphology. It is linked with insulin resistance through preferential abdominal fat accumulation that is worsened by obesity. Over the past two millennia, menstrual irregularity, male-type habitus and sub-infertility have been described in women and...

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PMID: 35012577
DOI: 10.1186/s12958-021-00878-y

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