Divergent pathophysiological drivers of polycystic ovary syndrome: insulin resistance independently fuels the hyperandrogenic phenotype whilst neuroendocrine factors dominate non-hyperandrogenic presentations.

Abstract excerpt

Background: Polycystic Ovary Syndrome (PCOS) manifests as a heterogeneous disorder, yet the extent to which metabolic dysfunction drives specific phenotypes independent of obesity remains debated. This study aimed to delineate the distinct clinical and pathophysiological characteristics of Hyperandrogenic (HA) versus 38 Non-Hyperandrogenic (Non-HA) phenotypes, with a specific focus on disentangling the roles of...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Adiposity
• Share to Androgens