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Article

Hydroxy Pentacyclic Triterpene Acid, Kaempferol, Inhibits the Human 5-Hydroxytryptamine Type 3A Receptor Activity.

International journal of molecular sciences - 4 Jan 2022

Lee Shinhui, Seol Hee-Soo, Eom Sanung, Lee Jaeeun, Kim Chaelin, Park Jong-Hwan, Kim Tae-Hwan, Lee Junho H

Abstract excerpt

Monoamine serotonin is a major neurotransmitter that acts on a wide range of central nervous system and peripheral nervous system functions and is known to have a role in various processes. Recently, it has been found that 5-HT is involved in cognitive and memory functions through interaction with cholinergic pathways. The natural flavonoid kaempferol (KAE) extracted from Cudrania tricuspidata is a secondary...

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Identifiers

PMID: 35008969
DOI: 10.3390/ijms23010544
PMCID: PMC8745345

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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