Article
A CLUSTER OF SARS-COV-2 DELTA VARIANT OF CONCERN ADDITIONALLY HARBORING F490S, NORTHERN LOMBARDY, ITALY.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Mar 2022
Novazzi Federica, Baj Andreina, Pasciuta Renee, Genoni Angelo, Drago Ferrante Francesca, Tripiciano Rosalia, Catanoso Giuseppe, Focosi Daniele, Maggi Fabrizio
Abstract excerpt
The Delta variant of concern (VOC) of SARS-CoV-2 has become dominant worldwide. In this article, we report a cluster caused by B.1.617.2 harboring the additional mutation of concern (MOC) F490S. We observed that 5 fully vaccinated subjects aged between 47 and 84 years were infected with this variant. The immune escape mutation F490S, first identified in the Lambda VOI, appears to impair vaccine efficacy and is...
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